TCT-531 INTRACORONARY VS. INTRAVENOUS ADENOSINE FOR FRACTIONAL FLOW RESERVE MEASUREMENT: A META-ANALYSIS

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Comparison of intracoronary versus intravenous administration of adenosine for measurement of coronary fractional flow reserve.

BACKGROUND Measurement of fractional flow reserve (FFR) constitutes the current gold standard to evaluate the hemodynamic significance of coronary stenoses. Limited data validate the intracoronary application of adenosine against standard intravenous infusion. We systematically compared FFR measurements during intracoronary and intravenous application of adenosine about agreement and reproducib...

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Intracoronary Versus Intravenous Adenosine-Induced Maximal Coronary Hyperemia for Fractional Flow Reserve Measurements

BACKGROUND Maximal hyperemia is the critical prerequisite for fractional flow reserve (FFR) assessment. Despite intravenous (IV) adenosine currently being the recommended approach, intracoronary (IC) administration of adenosine constitutes a valuable alternative in everyday practice. However, it is surprisingly unclear which IC strategy allows the achievement of FFR values that are comparable t...

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Intracoronary electrocardiogram ST segment shift evaluation during intravenous adenosine infusion: a comparison with fractional flow reserve.

BACKGROUND By measuring the pressure decline caused by coronary narrowing, fractional flow reserve (FFR) is an index of the physiological significance of a vessel stenosis. Intracoronary electrocardiogram (IC-ECG) recording from an angioplasty guidewire is more sensitive than standard ECG in detecting regional myocardial ischemia. The aim of the study was to assess if unipolar IC-ECG ST segment...

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Assessment of increasing intravenous adenosine dose in fractional flow reserve

BACKGROUND Effects of increased adenosine dose in the assessment of fractional flow reserve (FFR) were studied in relation to FFR results, hemodynamic effects and patient discomfort. FFR require maximal hyperemia mediated by adenosine. Standard dose is 140 μg/kg/min administrated intravenously. Higher doses are commonly used in clinical practice, but an extensive comparison between standard int...

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Adenosine-induced atrial fibrillation during fractional flow reserve measurement.

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2016

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2016.09.668